PMID- 7392035
OWN - NLM
STAT- MEDLINE
DCOM- 19800926
LR  - 20220321
IS  - 0022-2623 (Print)
IS  - 0022-2623 (Linking)
VI  - 23
IP  - 6
DP  - 1980 Jun
TI  - Relationship of octanol/water partition coefficient and molecular weight to rat 
      brain capillary permeability.
PG  - 682-4
AB  - The rat brain capillary permeability coefficient was determined for 27 compounds. 
      The relationship of permeability to octanol/water partition coefficient and 
      molecular weight was found to be predictable for drugs with molecular weights 
      less than 400.
FAU - Levin, V A
AU  - Levin VA
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - J Med Chem
JT  - Journal of medicinal chemistry
JID - 9716531
SB  - IM
MH  - Animals
MH  - *Blood-Brain Barrier
MH  - Brain/blood supply
MH  - Capillary Permeability
MH  - Male
MH  - Models, Biological
MH  - *Molecular Weight
MH  - Rats
MH  - Rats, Inbred F344
MH  - *Solubility
MH  - Structure-Activity Relationship
EDAT- 1980/06/01 00:00
MHDA- 1980/06/01 00:01
CRDT- 1980/06/01 00:00
PHST- 1980/06/01 00:00 [pubmed]
PHST- 1980/06/01 00:01 [medline]
PHST- 1980/06/01 00:00 [entrez]
AID - 10.1021/jm00180a022 [doi]
PST - ppublish
SO  - J Med Chem. 1980 Jun;23(6):682-4. doi: 10.1021/jm00180a022.