PMID- 7461472
OWN - NLM
STAT- MEDLINE
DCOM- 19810424
LR  - 20190501
IS  - 0017-5749 (Print)
IS  - 1458-3288 (Electronic)
IS  - 0017-5749 (Linking)
VI  - 22
IP  - 1
DP  - 1981 Jan
TI  - Description and basic cell kinetics of the murine pericryptal fibroblast sheath.
PG  - 19-24
AB  - The size of the pericryptal fibroblast sheath (PCFS) population was determined by 
      scoring serial sections. There are 38 and 124 PCFS cells per murine small 
      intestinal and colonic crypt, respectively. The cells of the PCFS are slightly 
      weighted towards the lower two-thirds of the crypt in their distribution. The 
      ratio of epithelial cells to PCFS cells is approximately 6.5:1. The in vivo cell 
      kinetics were analysed under control and stressed (fasted-refed) conditions. The 
      control labelling index increases from 8.9% in the small intestine and 7.0% in 
      the colon to peaks 49% and 113% respectively above these values 24 hours after 
      3HTdR administration. Labelling is observed at all crypt levels equally, and no 
      evidence of vertical migration of labelled PCFS cells was found. Colonic 
      epithelial and PCFS cells show a similar pattern of response to feeding after a 
      fast of 72 hours with respect to time, but a different distribution of response 
      in terms of crypt position.
FAU - Neal, J V
AU  - Neal JV
FAU - Potten, C S
AU  - Potten CS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Gut
JT  - Gut
JID - 2985108R
SB  - IM
MH  - Animals
MH  - Cell Count
MH  - Colon/*cytology
MH  - Epithelial Cells
MH  - Fibroblasts/cytology
MH  - Intestine, Small/*cytology
MH  - Male
MH  - Mice
MH  - Mice, Inbred DBA
MH  - Mitotic Index
MH  - Starvation/pathology
PMC - PMC1419298
EDAT- 1981/01/01 00:00
MHDA- 1981/01/01 00:01
PMCR- 1981/01/01
CRDT- 1981/01/01 00:00
PHST- 1981/01/01 00:00 [pubmed]
PHST- 1981/01/01 00:01 [medline]
PHST- 1981/01/01 00:00 [entrez]
PHST- 1981/01/01 00:00 [pmc-release]
AID - 10.1136/gut.22.1.19 [doi]
PST - ppublish
SO  - Gut. 1981 Jan;22(1):19-24. doi: 10.1136/gut.22.1.19.