PMID- 8024682 OWN - NLM STAT- MEDLINE DCOM- 19940811 LR - 20041117 IS - 0167-5699 (Print) IS - 0167-5699 (Linking) VI - 15 IP - 5 DP - 1994 May TI - Nervous tissue as an immune compartment: the dialect of the immune response in the CNS. PG - 218-24 AB - Here, Zsuzsa Fabry and colleagues address the question of whether the unique cellular environment of the central nervous system (CNS) contributes to the observed differences in immunological functions between the CNS and other organs. In particular, they discuss the significance within the CNS of the blood-brain barrier, the nonconstitutive expression of major histocompatibility complex (MHC) molecules, the unusual set of potential antigen-presenting and effector cells, and the production of immune or neuromediators from various cellular sources. FAU - Fabry, Z AU - Fabry Z AD - University of Iowa College of Medicine, Dept of Pathology, Iowa City 52242. FAU - Raine, C S AU - Raine CS FAU - Hart, M N AU - Hart MN LA - eng PT - Journal Article PT - Review PL - England TA - Immunol Today JT - Immunology today JID - 8008346 RN - 0 (Cell Adhesion Molecules) RN - 0 (Cytokines) SB - IM MH - Animals MH - Blood-Brain Barrier/immunology MH - Cell Adhesion Molecules/immunology MH - Central Nervous System/cytology/*immunology MH - Cytokines/biosynthesis MH - Humans MH - Major Histocompatibility Complex/immunology RF - 59 EDAT- 1994/05/01 00:00 MHDA- 1994/05/01 00:01 CRDT- 1994/05/01 00:00 PHST- 1994/05/01 00:00 [pubmed] PHST- 1994/05/01 00:01 [medline] PHST- 1994/05/01 00:00 [entrez] AID - 0167-5699(94)90247-X [pii] AID - 10.1016/0167-5699(94)90247-X [doi] PST - ppublish SO - Immunol Today. 1994 May;15(5):218-24. doi: 10.1016/0167-5699(94)90247-X.