PMID- 8157223 OWN - NLM STAT- MEDLINE DCOM- 19940518 LR - 20190830 IS - 0278-6915 (Print) IS - 0278-6915 (Linking) VI - 32 IP - 3 DP - 1994 Mar TI - Effect of dietary turmeric (Curcuma longa) on iron-induced lipid peroxidation in the rat liver. PG - 279-83 AB - Male Wistar rats were fed a control diet or the control diet supplemented with 1% (by weight) turmeric for 10 wk. In rats injected with 30 mg Fe2+/kg body weight, lipid peroxidation was 29 and 35% lower in liver homogenates and microsomes, respectively, of turmeric-fed rats than in those of rats fed the control diet. The activities of superoxide dismutase, catalase and glutathione peroxidase were higher (by 19, 19 and 20%, respectively) in liver homogenates of rats fed the turmeric-containing diet in comparison with the controls. These studies indicate that dietary turmeric lowers lipid peroxidation by enhancing the activities of antioxidant enzymes. FAU - Reddy, A C AU - Reddy AC AD - Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, India. FAU - Lokesh, B R AU - Lokesh BR LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Food Chem Toxicol JT - Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association JID - 8207483 RN - 0 (Ferrous Compounds) RN - 0 (Plant Extracts) RN - 0 (Reactive Oxygen Species) RN - 0 (Sesquiterpenes) RN - 39R4TAN1VT (ferrous sulfate) RN - 644-30-4 (alpha-curcumene) RN - 856YO1Z64F (turmeric extract) RN - EC 1.11.1.6 (Catalase) RN - EC 1.11.1.9 (Glutathione Peroxidase) RN - EC 1.15.1.1 (Superoxide Dismutase) RN - IT942ZTH98 (Curcumin) SB - IM MH - Animals MH - Catalase/metabolism MH - Curcuma MH - Curcumin/*analogs & derivatives/isolation & purification/pharmacology MH - Diet MH - Ferrous Compounds/*pharmacology MH - Glutathione Peroxidase/metabolism MH - Lipid Peroxidation/*drug effects MH - Liver/*drug effects/metabolism MH - Male MH - Microsomes, Liver/drug effects/metabolism MH - Plant Extracts/*pharmacology MH - Rats MH - Rats, Wistar MH - Reactive Oxygen Species MH - Sesquiterpenes MH - Superoxide Dismutase/metabolism EDAT- 1994/03/01 00:00 MHDA- 1994/03/01 00:01 CRDT- 1994/03/01 00:00 PHST- 1994/03/01 00:00 [pubmed] PHST- 1994/03/01 00:01 [medline] PHST- 1994/03/01 00:00 [entrez] AID - 0278-6915(94)90201-1 [pii] AID - 10.1016/0278-6915(94)90201-1 [doi] PST - ppublish SO - Food Chem Toxicol. 1994 Mar;32(3):279-83. doi: 10.1016/0278-6915(94)90201-1.