PMID- 8204911
OWN - NLM
STAT- MEDLINE
DCOM- 19940714
LR  - 20220224
IS  - 1059-910X (Print)
IS  - 1059-910X (Linking)
VI  - 27
IP  - 3
DP  - 1994 Feb 15
TI  - Dynamics of mitochondria in living cells: shape changes, dislocations, fusion, 
      and fission of mitochondria.
PG  - 198-219
AB  - Mitochondria are semi-autonomous organelles which are endowed with the ability to 
      change their shape (e.g., by elongation, shortening, branching, buckling, 
      swelling) and their location inside a living cell. In addition they may fuse or 
      divide. These dynamics are discussed. Dislocation of mitochondria may result from 
      their interaction with elements of the cytoskeleton, with microtubules in 
      particular, and from processes intrinsic to the mitochondria themselves. 
      Morphological criteria and differences in the fate of some mitochondria argue for 
      the presence of more than one mitochondrial population in some animal cells. 
      Whether these reflect genetic differences remains obscure. Emphasis is laid on 
      the methods for visualizing mitochondria in cells and following their behaviour. 
      Fluorescence methods provide unique possibilities because of their high resolving 
      power and because some of the mitochondria-specific fluorochromes can be used to 
      reveal the membrane potential. Fusion and fission often occur in short time 
      intervals within the same group of mitochondria. At sites of fusion of two 
      mitochondria material of the inner membrane, the matrix compartment seems to 
      accumulate. The original arrangement of the fusion partners is maintained for 
      some minutes. Fission is a dynamic event which, like fusion, in most cases 
      observed in vertebrate cell cultures is not a straight forward process but rather 
      requires several "trials" until the division finally occurs. Regarding fusion and 
      fission hitherto unpublished phase contrast micrographs, and electron micrographs 
      have been included.
FAU - Bereiter-Hahn, J
AU  - Bereiter-Hahn J
AD  - Cinematic Cell Research Group, Johann Wolfgang Goethe Universitat, Frankfurt am 
      Main, Germany.
FAU - Voth, M
AU  - Voth M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Microsc Res Tech
JT  - Microscopy research and technique
JID - 9203012
RN  - 0 (Cytoskeletal Proteins)
RN  - 0 (Fluorescent Dyes)
SB  - IM
MH  - Animals
MH  - Cell Movement
MH  - Cell Size
MH  - Cytoskeletal Proteins/metabolism
MH  - Fluorescent Dyes
MH  - HeLa Cells
MH  - Humans
MH  - Membrane Fusion/*physiology
MH  - Microscopy, Fluorescence
MH  - Microtubules/metabolism
MH  - Mitochondria/*metabolism/*ultrastructure
MH  - Xenopus
RF  - 242
EDAT- 1994/02/15 00:00
MHDA- 1994/02/15 00:01
CRDT- 1994/02/15 00:00
PHST- 1994/02/15 00:00 [pubmed]
PHST- 1994/02/15 00:01 [medline]
PHST- 1994/02/15 00:00 [entrez]
AID - 10.1002/jemt.1070270303 [doi]
PST - ppublish
SO  - Microsc Res Tech. 1994 Feb 15;27(3):198-219. doi: 10.1002/jemt.1070270303.