PMID- 8338236
OWN - NLM
STAT- MEDLINE
DCOM- 19930826
LR  - 20061115
IS  - 0003-276X (Print)
IS  - 0003-276X (Linking)
VI  - 236
IP  - 2
DP  - 1993 Jun
TI  - Dynamics of epithelial cells in the corpus of the mouse stomach. V. Behavior of 
      entero-endocrine and caveolated cells: general conclusions on cell kinetics in 
      the oxyntic epithelium.
PG  - 333-40
AB  - Entero-endocrine cells and the rare cells named caveolated or brush cells have 
      been examined in light microscopic radioautographs of the mouse corpus after 
      various periods of continuous 3H-thymidine infusion. Moreover a search for 
      immature forms and mitoses of these cells was undertaken in the electron 
      microscope. Entero-endocrine cells are present in the four regions of the 
      epithelial units, but their number is low in the pit, intermediate in the isthmus 
      and neck, and high in the base. The labeling pattern after continuous 
      3H-thymidine infusion indicates that these cells are produced in the isthmus from 
      undifferentiated granule-free cells presumed to be the stem cells of the 
      epithelium, and may retain a limited ability to divide. A few of the newly formed 
      entero-endocrine cells migrate to the pit, but the majority goes to the neck and, 
      from there, to the base where they are present in relatively high numbers. Little 
      information is available on the dynamics of caveolated cells. Since immature 
      forms are present in the isthmus and mature ones in the other regions, it is 
      concluded that they arise in the isthmus and migrate away in both directions. 
      Finally, concluding remarks are presented on the kinetics of each one of the cell 
      lineages described in this and the four previous articles.
FAU - Karam, S M
AU  - Karam SM
AD  - Department of Anatomy, McGill University, Montreal, Canada.
FAU - Leblond, C P
AU  - Leblond CP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Anat Rec
JT  - The Anatomical record
JID - 0370540
SB  - IM
MH  - Animals
MH  - Cell Differentiation
MH  - Cell Movement
MH  - Endocrine Glands/*cytology/ultrastructure
MH  - Epithelial Cells
MH  - Epithelium/ultrastructure
MH  - Male
MH  - Mice
MH  - Mice, Inbred C57BL
MH  - Microscopy, Electron
MH  - Stomach/*cytology/ultrastructure
EDAT- 1993/06/01 00:00
MHDA- 1993/06/01 00:01
CRDT- 1993/06/01 00:00
PHST- 1993/06/01 00:00 [pubmed]
PHST- 1993/06/01 00:01 [medline]
PHST- 1993/06/01 00:00 [entrez]
AID - 10.1002/ar.1092360206 [doi]
PST - ppublish
SO  - Anat Rec. 1993 Jun;236(2):333-40. doi: 10.1002/ar.1092360206.