PMID- 8524390
OWN - NLM
STAT- MEDLINE
DCOM- 19960123
LR  - 20240109
IS  - 0028-0836 (Print)
IS  - 0028-0836 (Linking)
VI  - 378
IP  - 6557
DP  - 1995 Dec 7
TI  - Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.
PG  - 578-83
AB  - The highly conserved protein gamma-tubulin is required for microtubule nucleation 
      in vivo. When viewed in the electron microscope, a highly purified gamma-tubulin 
      complex from Xenopus consisting of at least seven different proteins is seen to 
      have an open ring structure. This complex acts as an active 
      microtubule-nucleating unit which can cap the minus ends of microtubules in 
      vitro.
FAU - Zheng, Y
AU  - Zheng Y
AD  - Department of Biochemistry and Biophysics, University of California at San 
      Francisco 94143-0448, USA.
FAU - Wong, M L
AU  - Wong ML
FAU - Alberts, B
AU  - Alberts B
FAU - Mitchison, T
AU  - Mitchison T
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Nature
JT  - Nature
JID - 0410462
RN  - 0 (Tubulin)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Chromatography, Affinity
MH  - Microscopy, Electron
MH  - Microtubules/*metabolism/ultrastructure
MH  - Molecular Sequence Data
MH  - Oocytes/chemistry
MH  - Protein Conformation
MH  - Protein Structure, Secondary
MH  - Tubulin/*chemistry/isolation & purification/metabolism/ultrastructure
MH  - Xenopus
EDAT- 1995/12/07 00:00
MHDA- 1995/12/07 00:01
CRDT- 1995/12/07 00:00
PHST- 1995/12/07 00:00 [pubmed]
PHST- 1995/12/07 00:01 [medline]
PHST- 1995/12/07 00:00 [entrez]
AID - 10.1038/378578a0 [doi]
PST - ppublish
SO  - Nature. 1995 Dec 7;378(6557):578-83. doi: 10.1038/378578a0.