PMID- 9255069
OWN - NLM
STAT- MEDLINE
DCOM- 19970905
LR  - 20190909
IS  - 0968-0004 (Print)
IS  - 0968-0004 (Linking)
VI  - 22
IP  - 7
DP  - 1997 Jul
TI  - Phosphoinositide 3-kinases: a conserved family of signal transducers.
PG  - 267-72
AB  - Phosphoinositide 3-kinases (PI3Ks) generate lipids that are implicated in 
      receptor-stimulated signalling and in the regulation of membrane traffic. Several 
      distinct classes of PI3Ks have now been identified that have been conserved 
      throughout eukaryotic evolution. Potential signalling pathways downstream of 
      PI3Ks have been elucidated and PI3K function is now being characterised in 
      several model organisms.
FAU - Vanhaesebroeck, B
AU  - Vanhaesebroeck B
AD  - Ludwig Institute for Cancer Research, London, UK.
FAU - Leevers, S J
AU  - Leevers SJ
FAU - Panayotou, G
AU  - Panayotou G
FAU - Waterfield, M D
AU  - Waterfield MD
LA  - eng
SI  - GENBANK/M59835
SI  - GENBANK/M93252
SI  - GENBANK/S67334
SI  - GENBANK/U03279
SI  - GENBANK/U23476
SI  - GENBANK/U23477
SI  - GENBANK/U23478
SI  - GENBANK/U23480
SI  - GENBANK/U52192
SI  - GENBANK/U52193
SI  - GENBANK/U55772
SI  - GENBANK/U56101
SI  - GENBANK/U57843
SI  - GENBANK/U86453
SI  - GENBANK/U86587
SI  - GENBANK/X53531
SI  - GENBANK/X85368
SI  - GENBANK/X92892
SI  - GENBANK/X99912
SI  - GENBANK/Y08991
SI  - GENBANK/Y09070
SI  - GENBANK/Y10055
SI  - GENBANK/Y10742
SI  - GENBANK/Y10743
SI  - GENBANK/Y11312
SI  - GENBANK/Y13367
SI  - GENBANK/Y13892
SI  - GENBANK/Z29090
SI  - GENBANK/Z46973
SI  - GENBANK/Z69660
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Trends Biochem Sci
JT  - Trends in biochemical sciences
JID - 7610674
RN  - 0 (Membrane Lipids)
RN  - EC 2.7.1.- (Phosphatidylinositol 3-Kinases)
RN  - EC 2.7.1.- (Phosphotransferases (Alcohol Group Acceptor))
SB  - IM
MH  - Animals
MH  - Caenorhabditis elegans/enzymology
MH  - Dictyostelium/enzymology
MH  - Drosophila melanogaster/enzymology
MH  - Membrane Lipids/metabolism
MH  - Molecular Sequence Data
MH  - Phosphatidylinositol 3-Kinases
MH  - *Phosphotransferases (Alcohol Group Acceptor)/chemistry/classification/metabolism
MH  - *Signal Transduction
MH  - Substrate Specificity
RF  - 53
EDAT- 1997/07/01 00:00
MHDA- 1997/07/01 00:01
CRDT- 1997/07/01 00:00
PHST- 1997/07/01 00:00 [pubmed]
PHST- 1997/07/01 00:01 [medline]
PHST- 1997/07/01 00:00 [entrez]
AID - S096800049701061X [pii]
AID - 10.1016/s0968-0004(97)01061-x [doi]
PST - ppublish
SO  - Trends Biochem Sci. 1997 Jul;22(7):267-72. doi: 10.1016/s0968-0004(97)01061-x.